Incidence and severity of G6PI-induced arthritis are not increased in genetically distinct mouse strains upon aging

Abstract Background The incidence of rheumatoid arthritis is correlated with age. In this study, we analyzed the association of the incidence and severity of glucose-6-phosphate isomerase (G6PI)-induced arthritis with age in two different mouse strains. Methods Young and very old mice from two diffe...

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Bibliographic Details
Main Authors: Nico Andreas, Sylvia Müller, Nicole Templin, Paul M. Jordan, Harald Schuhwerk, Michael Müller, Jana Gerstmeier, Laura Miek, Saskia Andreas, Oliver Werz, Thomas Kamradt
Format: Article
Language:English
Published: BMC 2021-08-01
Series:Arthritis Research & Therapy
Subjects:
Age
FLS
SPM
Online Access:https://doi.org/10.1186/s13075-021-02596-7