Detection of Colorectal Adenomas Using a Bioactivatable Probe Specific for Matrix Metalloproteinase Activity

A significant proportion of colorectal adenomas, in particular those that lack an elevated growth component, continue to escape detection during endoscopic surveillance. Elevation of the activity of matrix metalloproteinases (MMPs), a large family of zinc endopeptidases, in adenomas serves as a bio...

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Bibliographic Details
Main Authors: Margie L. Clapper, Harvey H. Hensley, Wen-Chi L. Chang, Karthik Devarajan, Minhhuyen T. Nguyen, Harry S. Cooper
Format: Article
Language:English
Published: Elsevier 2011-08-01
Series:Neoplasia: An International Journal for Oncology Research
Online Access:http://www.sciencedirect.com/science/article/pii/S1476558611800035