1H NMR-Based Metabolomics Coupled With Molecular Docking Reveal the Anti-Diabetic Effects and Potential Active Components of Berberis vernae on Type 2 Diabetic Rats

1H NMR-Based Metabolomics Coupled With Molecular Docking Reveal the Anti-Diabetic Effects and Potential Active Components of Berberis vernae on Type 2 Diabetic Rats

The dried stem bark of Berberis vernae C.K.Schneid., known as “Xiao-bo-pi” in Chinese, is a representative anti-diabetic herb in traditional Tibetan medical system. However, its anti-diabetic mechanisms and active components remain unclear. In this study, 1H NMR-based metabolomics, biochemistry assa...

Full description

Bibliographic Details
Main Authors: Qi Li, Chengcheng Zhao, Yunsen Zhang, Huan Du, Tong Xu, Xinmei Xu, Jing Zhang, Tingting Kuang, Xianrong Lai, Gang Fan, Yi Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-06-01
Series:Frontiers in Pharmacology
Subjects:
Berberis vernae
herbal medicine
type 2 diabetes
metabolomics
molecular docking
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2020.00932/full

Internet

https://www.frontiersin.org/article/10.3389/fphar.2020.00932/full

Similar Items