Evaluation of formulation and effects of process parameters on drug release and mechanical properties of tramadol hydrocloride sustained release matrix tablets

Evaluation of formulation and effects of process parameters on drug release and mechanical properties of tramadol hydrocloride sustained release matrix tablets

This study investigates using of high molecular weight polyethylene oxide (PEO WSR Coagulant) for the preparation of sustained release matrix tablets containing high dose, highly water soluble drug, tramadol HCl. Proportion of PEO polymer, type of insoluble filler, proportion of tramadol HC...

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Bibliographic Details
Main Authors: Nikolić Nenad D., Medarević Đorđe P., Ibrić Svetlana R., Đurić Zorica R.
Format: Article
Language:English
Published: Association of Chemical Engineers of Serbia 2015-01-01
Series:Hemijska Industrija
Subjects:
tramadol HCl
matrix tablets
PEO WSR Coagulant
drug release
mechanical properties of tablets
Online Access:http://www.doiserbia.nb.rs/img/doi/0367-598X/2015/0367-598X1400069N.pdf

Internet

http://www.doiserbia.nb.rs/img/doi/0367-598X/2015/0367-598X1400069N.pdf

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