Effects of primary microglia and astrocytes on neural stem cells in in vitro and in vivo models of ischemic stroke

Effects of primary microglia and astrocytes on neural stem cells in in vitro and in vivo models of ischemic stroke

Transplantation of neural stem cells (NSCs) can protect neurons in animal stroke models; however, their low rates of survival and neuronal differentiation limit their clinical application. Glial niches, an important location of neural stem cells, regulate survival, proliferation and differentiation...

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Bibliographic Details
Main Authors: Sheng-Jun Wen, Xi-Min Zheng, Li-Fen Liu, Na-Na Li, Hai-An Mao, Liang Huang, Qiong-Lan Yuan
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2021-01-01
Series:Neural Regeneration Research
Subjects:
astrocytes; glutamate; microglia; neural stem cells; neurogenesis; neurons; peroxide; repair; stroke
Online Access:http://www.nrronline.org/article.asp?issn=1673-5374;year=2021;volume=16;issue=9;spage=1677;epage=1685;aulast=Wen

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http://www.nrronline.org/article.asp?issn=1673-5374;year=2021;volume=16;issue=9;spage=1677;epage=1685;aulast=Wen

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