Rhinovirus Load Is High despite Preserved Interferon-β Response in Cystic Fibrosis Bronchial Epithelial Cells.

Lung disease in cystic fibrosis (CF) is often exacerbated following acute upper respiratory tract infections caused by the human rhinovirus (HRV). Pathophysiology of these exacerbations is presently unclear and may involve deficient innate antiviral or exaggerated inflammatory responses in CF airway...

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Bibliographic Details
Main Authors: Nurlan Dauletbaev, Mithun Das, Maria Cammisano, He Chen, Sareen Singh, Cora Kooi, Richard Leigh, Trevor Beaudoin, Simon Rousseau, Larry C Lands
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4658124?pdf=render