Mechanism of increased risk of insulin resistance in aging skeletal muscle

Abstract As age increases, the risk of developing type 2 diabetes increases, which is associated with senile skeletal muscle dysfunction. During skeletal muscle aging, mitochondrial dysfunction, intramyocellular lipid accumulation, increased inflammation, oxidative stress, modified activity of insul...

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Bibliographic Details
Main Authors: Jian Shou, Pei-Jie Chen, Wei-Hua Xiao
Format: Article
Language:English
Published: BMC 2020-02-01
Series:Diabetology & Metabolic Syndrome
Subjects:
Online Access:https://doi.org/10.1186/s13098-020-0523-x