Oncoglabrinol C, a new flavan from Oncocalyx glabratus protects endothelial cells against oxidative stress and apoptosis, and modulates hepatic CYP3A4 activity

Oncoglabrinol C, a new flavan from Oncocalyx glabratus protects endothelial cells against oxidative stress and apoptosis, and modulates hepatic CYP3A4 activity

Active herbal or natural compounds have high chemical diversity and specificity than synthetic drugs. Recently, we have validated the hypoglycemic salutation of Oncocalyx glabratus in rodent model, and demonstrated the activation of PPARα/γ by its newly ioslated flavan derivative Oncoglabrinol C (5,...

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Bibliographic Details
Main Authors: Mohammad K. Parvez, Mohammed S. Al-Dosari, Sarfaraz Ahmed, Md. Tabish Rehman, Adnan J. Al-Rehaily, Mohammed F. Alajmi
Format: Article
Language:English
Published: Elsevier 2020-06-01
Series:Saudi Pharmaceutical Journal
Subjects:
Oncocalyx glabratus
Oncoglabrinol C
Apoptosis
Caspase
CYP3A4
Online Access:http://www.sciencedirect.com/science/article/pii/S1319016420300839

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http://www.sciencedirect.com/science/article/pii/S1319016420300839

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