A clinical trial of non-invasive imaging with an anti-HIV antibody labelled with copper-64 in people living with HIV and uninfected controls

A clinical trial of non-invasive imaging with an anti-HIV antibody labelled with copper-64 in people living with HIV and uninfected controls

Background: A research priority in finding a cure for HIV is to establish methods to accurately locate and quantify where and how HIV persists in people living with HIV (PLWH) receiving suppressive antiretroviral therapy (ART). Infusing copper-64 (64Cu) radiolabelled broadly neutralising antibodies...

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Bibliographic Details
Main Authors: James H. McMahon, Jennifer M. Zerbato, Jillian S.Y. Lau, Jaclyn L. Lange, Michael Roche, Carolin Tumpach, Ashanti Dantanarayana, Ajantha Rhodes, Judy Chang, Thomas A. Rasmussen, Charlene A. Mackenzie, Karen Alt, Michelle Hagenauer, Janine Roney, Jessica O‘Bryan, Alexandra Carey, Richard McIntyre, Paul Beech, Graeme J. O'Keefe, Christian W. Wichmann, Fiona E. Scott, Nancy Guo, Sze-Ting Lee, Zhanqi Liu, Marina Caskey, Michel C. Nussenzweig, Paul S. Donnelly, Gary Egan, Christoph E. Hagemeyer, Andrew M. Scott, Sharon R. Lewin
Format: Article
Language:English
Published: Elsevier 2021-03-01
Series:EBioMedicine
Subjects:
HIV
Imaging
Clinical trial
PET scan
Broadly neutralising antibodies
Online Access:http://www.sciencedirect.com/science/article/pii/S2352396421000451

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http://www.sciencedirect.com/science/article/pii/S2352396421000451

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