All-Trans Retinoic Acid Induces DU145 Cell Cycle Arrest through Cdk5 Activation

All-Trans Retinoic Acid Induces DU145 Cell Cycle Arrest through Cdk5 Activation

Background/Aims: All-trans retinoic acid (ATRA), the active form of vitamin A, plays an important role in the growth arrest of numerous types of cancer cells. It has been indicated that cyclin-dependent kinase 5 (Cdk5) activity can be affected by ATRA treatment. Our previous results demonstrate the...

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Bibliographic Details
Main Authors: Eugene Lin, Mei-Chih Chen, Chih-Yang Huang, Shih-Lan Hsu, William J. Huang, Mao-Sheng Lin, Jungle Chi-Hsiang Wu, Ho Lin
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2014-05-01
Series:Cellular Physiology and Biochemistry
Subjects:
ATRA
Cdk5
p27
Prostate cancer
Cell cycle arrest
Online Access:http://www.karger.com/Article/FullText/358724

Internet

http://www.karger.com/Article/FullText/358724

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