MiR-137 Suppresses Triple-Negative Breast Cancer Stemness and Tumorigenesis by Perturbing BCL11A-DNMT1 Interaction

MiR-137 Suppresses Triple-Negative Breast Cancer Stemness and Tumorigenesis by Perturbing BCL11A-DNMT1 Interaction

Background/Aims: Triple negative breast cancer (TNBC) is resistant to conventional chemotherapy due to high proportions of cancer stem cells (CSCs). The aim of this study is to unravel the miR-137-mediated regulatory mechanism of B-cell lymphoma/leukemia 11A (BCL11A) in TNBC. Methods: A corhort of 3...

Full description

Bibliographic Details
Main Authors: Feiyu Chen, Na Luo, Yu Hu, Xin Li, Kejing  Zhang
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2018-07-01
Series:Cellular Physiology and Biochemistry
Subjects:
Mir-137
B-cell lymphoma/leukemia 11A (BCL11A)
Triple negative breast cancer
Breast cancer stem cells
DNMT1
Online Access:https://www.karger.com/Article/FullText/491526

Internet

https://www.karger.com/Article/FullText/491526

Similar Items