Contribution of LTi and TH17 cells to B cell aggregate formation in the central nervous system in a mouse model of multiple sclerosis

Contribution of LTi and TH17 cells to B cell aggregate formation in the central nervous system in a mouse model of multiple sclerosis

Abstract Background In a subgroup of patients suffering from progressive multiple sclerosis (MS), which is an inflammation-mediated neurodegenerative disease of the central nervous system (CNS), B cell aggregates were discovered within the meninges. Occurrence of these structures was associated with...

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Bibliographic Details
Main Authors: Verena Schropp, Jörn Rohde, Damiano M. Rovituso, Samir Jabari, Richa Bharti, Stefanie Kuerten
Format: Article
Language:English
Published: BMC 2019-05-01
Series:Journal of Neuroinflammation
Subjects:
EAE
LTi cells
MP4
MS
TH17 cells
Online Access:http://link.springer.com/article/10.1186/s12974-019-1500-x

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http://link.springer.com/article/10.1186/s12974-019-1500-x

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