Early Genotoxic and Cytotoxic Effects of the Toxic Dinoflagellate Prorocentrum lima in the Mussel Mytilus galloprovincialis

Early Genotoxic and Cytotoxic Effects of the Toxic Dinoflagellate Prorocentrum lima in the Mussel Mytilus galloprovincialis

Okadaic acid (OA) and dinophysistoxins (DTXs) are the main toxins responsible for diarrhetic shellfish poisoning (DSP) intoxications during harmful algal blooms (HABs). Although the genotoxic and cytotoxic responses to OA have been evaluated in vitro, the in vivo effects of these toxins have not yet...

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Bibliographic Details
Main Authors: María Verónica Prego-Faraldo, Vanessa Valdiglesias, Blanca Laffon, Josefina Mendez, Jose M. Eirin-Lopez
Format: Article
Language:English
Published: MDPI AG 2016-05-01
Series:Toxins
Subjects:
bivalve molluscs
DSP toxins
okadaic acid
DNA damage
oxidative DNA damage
cytotoxicity
comet assay
flow cytometry
OGG1 enzyme
Online Access:http://www.mdpi.com/2072-6651/8/6/159

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http://www.mdpi.com/2072-6651/8/6/159

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