Rapid reverse phase-HPLC assay of HMG-CoA reductase activity

Radioisotope-based and mass spectrometry coupled to chromatographic techniques are the conventional methods for monitoring HMG-CoA reductase (HMGR) activity. Irrespective of offering adequate sensitivity, these methods are often cumbersome and time-consuming, requiring the handling of radiolabeled c...

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Bibliographic Details
Main Authors: Matteo Mozzicafreddo, Massimiliano Cuccioloni, Anna Maria Eleuteri, Mauro Angeletti
Format: Article
Language:English
Published: Elsevier 2010-08-01
Series:Journal of Lipid Research
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520370838