Vitamin B12 Deficiency Induces Imbalance in Melanocytes Homeostasis—A Cellular Basis of Hypocobalaminemia Pigmentary Manifestations

Vitamin B12 Deficiency Induces Imbalance in Melanocytes Homeostasis—A Cellular Basis of Hypocobalaminemia Pigmentary Manifestations

Vitamin B12 deficiency causes significant changes in cellular metabolism leading to various clinical symptoms, such as hematological, psychiatric, and neurological disorders. We hypothesize that skin pigmentation disorders may be a diagnostically important manifestation of vitamin B12 deficiency, ho...

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Bibliographic Details
Main Authors: Zuzanna Rzepka, Michalina Respondek, Jakub Rok, Artur Beberok, Keith ó Proinsias, Dorota Gryko, Dorota Wrześniok
Format: Article
Language:English
Published: MDPI AG 2018-09-01
Series:International Journal of Molecular Sciences
Subjects:
vitamin B12
cobalamin deficiency
hyperpigmentations
melanogenesis
oxidative stress
Online Access:http://www.mdpi.com/1422-0067/19/9/2845

Internet

http://www.mdpi.com/1422-0067/19/9/2845

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