Tumor Mesenchymal Stromal Cells Regulate Cell Migration of Atypical Teratoid Rhabdoid Tumor through Exosome-Mediated miR155/SMARCA4 Pathway

Tumor Mesenchymal Stromal Cells Regulate Cell Migration of Atypical Teratoid Rhabdoid Tumor through Exosome-Mediated miR155/SMARCA4 Pathway

Atypical teratoid/rhabdoid tumor (ATRT) is a rare pediatric brain tumor with extremely high aggressiveness and poor prognosis. The tumor microenvironment is regulated by a complex interaction among distinct cell types, yet the crosstalk between tumor-associated mesenchymal stem cells (tMSCs) and na&...

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Bibliographic Details
Main Authors: Yi-Ping Yang, Phan Nguyen Nhi Nguyen, Hsin-I Ma, Wen-Jin Ho, Yi-Wei Chen, Yueh Chien, Aliaksandr A. Yarmishyn, Pin-I Huang, Wen-Liang Lo, Chien-Ying Wang, Yung-Yang Liu, Yi-Yen Lee, Chien-Min Lin, Ming-Teh Chen, Mong-Lien Wang
Format: Article
Language:English
Published: MDPI AG 2019-05-01
Series:Cancers
Subjects:
atypical teratoid/rhabdoid tumor
tumor-associated mesenchymal stem cells
miR155
SMARCA4
exosome
Online Access:https://www.mdpi.com/2072-6694/11/5/720

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https://www.mdpi.com/2072-6694/11/5/720

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