Lowering the increased intracellular pH of human‐induced pluripotent stem cell‐derived endothelial cells induces formation of mature Weibel‐Palade bodies

Lowering the increased intracellular pH of human‐induced pluripotent stem cell‐derived endothelial cells induces formation of mature Weibel‐Palade bodies

Abstract Differentiation of human‐induced pluripotent stem cells (hiPSCs) into vascular endothelium is of great importance to tissue engineering, disease modeling, and use in regenerative medicine. Although differentiation of hiPSCs into endothelial‐like cells (hiPSC‐derived endothelial cells [hiPSC...

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Bibliographic Details
Main Authors: Gesa L. Tiemeier, Rozemarijn deKoning, Gangqi Wang, Sarantos Kostidis, Rosalie G. J. Rietjens, Wendy M. P. J. Sol, Sébastien J. Dumas, Martin Giera, Cathelijne W. van denBerg, Jeroen C. J. Eikenboom, Bernard M. van denBerg, Peter Carmeliet, Ton J. Rabelink
Format: Article
Language:English
Published: Wiley 2020-07-01
Series:Stem Cells Translational Medicine
Subjects:
cell therapy
glycolysis
induced pluripotent stem cell‐derived endothelial cells
von Willebrand factor
Weibel‐Palade bodies
Online Access:https://doi.org/10.1002/sctm.19-0392

Internet

https://doi.org/10.1002/sctm.19-0392

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