Upgrading ketone synthesis direct from carboxylic acids and organohalides

Due to their abundance and importance in organic chemistry, development of methods for ketone synthesis is essential. Here, the authors report a photoredox, nickel and phosphoranyl radical synergistic cross-electrophile coupling of aromatic acids and aryl/alkyl bromides to directly synthesise ketone...

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Bibliographic Details
Main Authors: Rehanguli Ruzi, Kai Liu, Chengjian Zhu, Jin Xie
Format: Article
Language:English
Published: Nature Publishing Group 2020-07-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-020-17224-2