Clinical expression of cystic fibrosis in a large cohort of Italian siblings

Clinical expression of cystic fibrosis in a large cohort of Italian siblings

Abstract Background A clinical heterogeneity was reported in patients with Cystic Fibrosis (CF) with the same CFTR genotype and between siblings with CF. Methods We investigated all clinical aspects in a cohort of 101 pairs of siblings with CF (including 6 triplets) followed since diagnosis. Results...

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Bibliographic Details
Main Authors: Vito Terlizzi, Marco Lucarelli, Donatello Salvatore, Adriano Angioni, Arianna Bisogno, Cesare Braggion, Roberto Buzzetti, Vincenzo Carnovale, Rosaria Casciaro, Giuseppe Castaldo, Natalia Cirilli, Mirella Collura, Carla Colombo, Antonella Miriam Di Lullo, Ausilia Elce, Vincenzina Lucidi, Elisa Madarena, Rita Padoan, Serena Quattrucci, Valeria Raia, Manuela Seia, Lisa Termini, Federica Zarrilli
Format: Article
Language:English
Published: BMC 2018-12-01
Series:BMC Pulmonary Medicine
Subjects:
CFTR
Genotype
Phenotype
Modifier genes
FEV1
Pseudomonas aeruginosa
Online Access:http://link.springer.com/article/10.1186/s12890-018-0766-6

Internet

http://link.springer.com/article/10.1186/s12890-018-0766-6

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