FGF23, Hypophosphatemia, and Emerging Treatments

ABSTRACT FGF23 is an important hormonal regulator of phosphate homeostasis. Together with its co‐receptor Klotho, it modulates phosphate reabsorption and both 1α‐hydroxylation and 24‐hydroxylation in the renal proximal tubules. The most common FGF23‐mediated hypophosphatemia is X‐linked hypophosphat...

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Bibliographic Details
Main Authors: Erik A Imel, Andrew Biggin, Aaron Schindeler, Craig F Munns
Format: Article
Language:English
Published: Wiley 2019-08-01
Series:JBMR Plus
Subjects:
XLH
Online Access:https://doi.org/10.1002/jbm4.10190