PLGA Biodegradable Nanoparticles Containing Perphenazine or Chlorpromazine Hydrochloride: Effect of Formulation and Release

PLGA Biodegradable Nanoparticles Containing Perphenazine or Chlorpromazine Hydrochloride: Effect of Formulation and Release

In our study, poly(dl-lactide-co-glycolide) (PLGA) nanoparticles loaded with perphenazine (PPH) and chlorpromazine hydrochloride (CPZ-HCl) were formulated by emulsion solvent evaporation technique. The effect of various processing variables, including PLGA concentration, theoretical drug loading, po...

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Bibliographic Details
Main Authors: Mohammed Halayqa, Urszula Domańska
Format: Article
Language:English
Published: MDPI AG 2014-12-01
Series:International Journal of Molecular Sciences
Subjects:
perphenazine
chlorpromazine hydrochloride
psychotic drugs
experimental nanomedicine
PLGA
physicochemical properties of nanoparticles
controlled drug delivery
Online Access:http://www.mdpi.com/1422-0067/15/12/23909

Internet

http://www.mdpi.com/1422-0067/15/12/23909

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