Senescence Inducer Shikonin ROS-Dependently Suppressed Lung Cancer Progression

Senescence Inducer Shikonin ROS-Dependently Suppressed Lung Cancer Progression

Lung adenocarcinoma (LAC), predominant subclassfication of lung cancer, leads high incidence and mortality annually worldwide. During the premalignant transition from lung adenomas to LAC, cellular senescence is regard as a critical physiological barrier against tumor progression. Nevertheless, the...

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Bibliographic Details
Main Authors: Hongming Zheng, Qiuju Huang, Suchao Huang, Xia Yang, Ting Zhu, Wensheng Wang, Haojia Wang, Shugui He, Liyan Ji, Ying Wang, Xiaoxiao Qi, Zhongqiu Liu, Linlin Lu
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-05-01
Series:Frontiers in Pharmacology
Subjects:
shikonin
lung cancer
senescence
ROS
DNA damage
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2018.00519/full

Internet

https://www.frontiersin.org/article/10.3389/fphar.2018.00519/full

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