Construction of microRNA functional families by a mixture model of position weight matrices

MicroRNAs (miRNAs) are small regulatory molecules that repress the translational processes of their target genes by binding to their 3′ untranslated regions (3′ UTRs). Because the target genes are predominantly determined by their sequence complementarity to the miRNA seed regions (nucleotides 2–7)...

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Bibliographic Details
Main Authors: Je-Keun Rhee, Soo-Yong Shin, Byoung-Tak Zhang
Format: Article
Language:English
Published: PeerJ Inc. 2013-10-01
Series:PeerJ
Subjects:
Online Access:https://peerj.com/articles/199.pdf