Hormonal-receptor positive breast cancer: IL-6 augments invasion and lymph node metastasis via stimulating cathepsin B expression

Hormonal-receptor positive breast cancer: IL-6 augments invasion and lymph node metastasis via stimulating cathepsin B expression

Hormonal-receptor positive (HRP) breast cancer patients with positive metastatic axillary lymph nodes are characterized by poor prognosis and increased mortality rate. The mechanisms by which cancer cells invade lymph nodes have not yet been fully explored. Several studies have shown that expression...

Full description

Bibliographic Details
Main Authors: Sherif A. Ibrahim, Eslam A. El-Ghonaimy, Hebatallah Hassan, Noha Mahana, Mahmoud Abdelbaky Mahmoud, Tahani El-Mamlouk, Mohamed El-Shinawi, Mona M. Mohamed
Format: Article
Language:English
Published: Elsevier 2016-09-01
Series:Journal of Advanced Research
Subjects:
Hormonal-receptor positive breast cancer
IL-6
Cathepsin B
Invasion
Lymph node metastasis
Epithelial-mesenchymal transition
Online Access:http://www.sciencedirect.com/science/article/pii/S2090123216300467

Internet

http://www.sciencedirect.com/science/article/pii/S2090123216300467

Similar Items