Concerted regulation of retinal pigment epithelium basement membrane and barrier function by angiocrine factors

Concerted regulation of retinal pigment epithelium basement membrane and barrier function by angiocrine factors

Establishment of the outer blood-retina barrier is a hallmark of retinal development but the contribution of choroid endothelial cells (ECs) is not known. Here the authors show in the developing mouse retina that ECs remodel the basement membrane and lead to enhanced barrier function of retinal epit...

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Bibliographic Details
Main Authors: Ignacio Benedicto, Guillermo L. Lehmann, Michael Ginsberg, Daniel J. Nolan, Rohan Bareja, Olivier Elemento, Zelda Salfati, Nazia M. Alam, Glen T. Prusky, Pierre Llanos, Sina Y. Rabbany, Arvydas Maminishkis, Sheldon S. Miller, Shahin Rafii, Enrique Rodriguez-Boulan
Format: Article
Language:English
Published: Nature Publishing Group 2017-05-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/ncomms15374

Internet

https://doi.org/10.1038/ncomms15374

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