Restorative effect of adipose tissue-derived stem cells on impaired hepatocytes through Notch signaling in non-alcoholic steatohepatitis mice

Restorative effect of adipose tissue-derived stem cells on impaired hepatocytes through Notch signaling in non-alcoholic steatohepatitis mice

Adipose tissue-derived stem cells (ADSCs) have been suggested as a novel treatment for non-alcoholic steatohepatitis (NASH); however, the mechanisms underlying their therapeutic effect remain poorly understood. In this study, we aimed to investigate the association of Notch signaling, which is cruci...

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Bibliographic Details
Main Authors: Kosuke Ishida, Akihiro Seki, Kazunori Kawaguchi, Alessandro Nasti, Masatoshi Yamato, Hiiro Inui, Takuya Komura, Taro Yamashita, Kuniaki Arai, Tatsuya Yamashita, Eishiro Mizukoshi, Masao Honda, Takashi Wada, Kenichi Harada, Shuichi Kaneko, Yoshio Sakai
Format: Article
Language:English
Published: Elsevier 2021-07-01
Series:Stem Cell Research
Subjects:
Notch
Adipose tissue-derived stem cells
Non-alcoholic steatohepatitis
Apoptosis
Online Access:http://www.sciencedirect.com/science/article/pii/S1873506121002725

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http://www.sciencedirect.com/science/article/pii/S1873506121002725

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