Combined Metabolomic Analysis of Plasma and Tissue Reveals a Prognostic Risk Score System and Metabolic Dysregulation in Esophageal Squamous Cell Carcinoma

Combined Metabolomic Analysis of Plasma and Tissue Reveals a Prognostic Risk Score System and Metabolic Dysregulation in Esophageal Squamous Cell Carcinoma

Background: Esophageal squamous cell carcinoma (ESCC) is a gastrointestinal malignancy with a poor prognosis. Although studies have shown metabolic reprogramming to be linked to ESCC development, no prognostic metabolic biomarkers or potential therapeutic metabolic targets have been identified.Metho...

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Bibliographic Details
Main Authors: Zhongjian Chen, Yalan Dai, Xiancong Huang, Keke Chen, Yun Gao, Na Li, Ding Wang, Aiping Chen, Qingxia Yang, Yanjun Hong, Su Zeng, Weimin Mao
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-08-01
Series:Frontiers in Oncology
Subjects:
esophageal squamous cell carcinoma (ESCC)
metabolomics
risk score
prognosis
diagnosis
indoleamine 2
Online Access:https://www.frontiersin.org/article/10.3389/fonc.2020.01545/full

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https://www.frontiersin.org/article/10.3389/fonc.2020.01545/full

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