Forward Chemical Genetics in Yeast for Discovery of Chemical Probes Targeting Metabolism

The many virtues that made the yeast Saccharomyces cerevisiae a dominant model organism for genetics and molecular biology, are now establishing its role in chemical genetics. Its experimental tractability (i.e., rapid doubling time, simple culture conditions) and the availability of powerful tools...

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Bibliographic Details
Main Authors: Marie Evangelista, Curt Scharfe, Ulrich Schlecht, Robert St.Onge
Format: Article
Language:English
Published: MDPI AG 2012-11-01
Series:Molecules
Subjects:
Online Access:http://www.mdpi.com/1420-3049/17/11/13098