Microglial Activation After Systemic Stimulation With Lipopolysaccharide and Escherichia coli

Background: Microglial activation after systemic infection has been suggested to mediate sepsis-associated delirium. A systematic review of animal studies suggested distinct differences between microglial activation after systemic challenge with live bacteria and lipopolysaccharide (LPS). Here, we d...

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Main Authors: Inge C. M. Hoogland, Dunja Westhoff, Joo-Yeon Engelen-Lee, Jeroen Melief, Mercedes Valls Serón, Judith H. M. P. Houben-Weerts, Inge Huitinga, David J. van Westerloo, Tom van der Poll, Willem A. van Gool, Diederik van de Beek
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-04-01
Series:Frontiers in Cellular Neuroscience
Subjects:
Online Access:http://journal.frontiersin.org/article/10.3389/fncel.2018.00110/full