Impact of leucocyte depletion and prion reduction filters on TSE blood borne transmission.

Impact of leucocyte depletion and prion reduction filters on TSE blood borne transmission.

The identification in the UK of 4 v-CJD infected patients thought to be due to the use of transfused Red Blood Cell units prepared from blood of donors incubating v-CJD raised major concerns in transfusion medicine. The demonstration of leucocyte associated infectivity using various animal models of...

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Bibliographic Details
Main Authors: Caroline Lacroux, Daisy Bougard, Claire Litaise, Hugh Simmons, Fabien Corbiere, Dominique Dernis, René Tardivel, Nathalie Morel, Stephanie Simon, Séverine Lugan, Pierrette Costes, Jean Louis Weisbecker, François Schelcher, Jacques Grassi, Joliette Coste, Olivier Andréoletti
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3409224?pdf=render

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http://europepmc.org/articles/PMC3409224?pdf=render

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