Regulatory T cells and IL-10 independently counterregulate cytotoxic T lymphocyte responses induced by transcutaneous immunization.

Regulatory T cells and IL-10 independently counterregulate cytotoxic T lymphocyte responses induced by transcutaneous immunization.

The imidazoquinoline derivate imiquimod induces inflammatory responses and protection against transplanted tumors when applied to the skin in combination with a cognate peptide epitope (transcutaneous immunization, TCI). Here we investigated the role of regulatory T cells (T(reg)) and the suppressiv...

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Bibliographic Details
Main Authors: Pamela Stein, Michael Weber, Steve Prüfer, Beate Schmid, Edgar Schmitt, Hans-Christian Probst, Ari Waisman, Peter Langguth, Hansjörg Schild, Markus P Radsak
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3218067?pdf=render

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http://europepmc.org/articles/PMC3218067?pdf=render

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