Targeted disruption of the mouse cis-retinol dehydrogenase gene: visual and nonvisual functions

It has been proposed that cis-retinol dehydrogenase (cRDH) acts within the body to catalyze the oxidation of 9-cis-retinol, an oxidative step needed for 9-cis-retinoic acid synthesis, the oxidation of 11-cis-retinol [an oxidative step needed for 11-cis-retinal (visual chromophore) synthesis], and 3...

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Bibliographic Details
Main Authors: Enyuan Shang, Katherine Lai, Alan I. Packer, Jisun Paik, William S. Blaner, Milena de Morais Vieira, Peter Gouras, Debra J. Wolgemuth
Format: Article
Language:English
Published: Elsevier 2002-04-01
Series:Journal of Lipid Research
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520314887