AMP deaminase 3 deficiency enhanced 5'-AMP induction of hypometabolism.

A hypometabolic state can be induced in mice by 5'-AMP administration. Previously we proposed that an underlying mechanism for this hypometabolism is linked to reduced erythrocyte oxygen transport function due to 5'-AMP uptake altering the cellular adenylate equilibrium. To test this hypot...

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Bibliographic Details
Main Authors: Isadora Susan Daniels, William G O Brien, Vinay Nath, Zhaoyang Zhao, Cheng Chi Lee
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3774621?pdf=render