Protective effect of compound Danshen (Salvia miltiorrhiza) dripping pills alone and in combination with carbamazepine on kainic acid-induced temporal lobe epilepsy and cognitive impairment in rats

Protective effect of compound Danshen (Salvia miltiorrhiza) dripping pills alone and in combination with carbamazepine on kainic acid-induced temporal lobe epilepsy and cognitive impairment in rats

Context: Temporal lobe epilepsy (TLE) is resistant to antiepileptic drugs (AEDs) and is associated with cognitive impairment. The modern Chinese medicine, compound Danshen dripping pills (CDDP), is clinically effective in treating epilepsy and improving cognitive impairment. Objective: This study ev...

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Bibliographic Details
Main Authors: Chen Jia, Shanshan Han, Liming Wei, Xiangji Dang, Qianqian Niu, Mengyu Chen, Boqun Cao, Yuting Liu, Haisheng Jiao
Format: Article
Language:English
Published: Taylor & Francis Group 2018-01-01
Series:Pharmaceutical Biology
Subjects:
intractable epilepsy
antiepileptic drugs
traditional chinese medicine
hippocampal ca3 area
glial cell line-derived neurotrophic factor
anti-apoptosis
Online Access:http://dx.doi.org/10.1080/13880209.2018.1432665

Internet

http://dx.doi.org/10.1080/13880209.2018.1432665

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