Luteolin alleviates neuroinflammation via downregulating the TLR4/TRAF6/NF-κB pathway after intracerebral hemorrhage

Luteolin alleviates neuroinflammation via downregulating the TLR4/TRAF6/NF-κB pathway after intracerebral hemorrhage

The activation of microglia and inflammatory responses is essential for the process of intracerebral hemorrhage (ICH)-induced secondary brain injury (SBI). In this study, we investigated the effects of luteolin on ICH-induced SBI and the potential mechanisms. Autologous blood was injected to establis...

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Bibliographic Details
Main Authors: Yi Yang, Xin Tan, Jianguo Xu, Tianyi Wang, Tianyu Liang, Xiang Xu, Cheng Ma, Zhongmou Xu, Wenjie Wang, Haiying Li, Haitao Shen, Xiang Li, Wanli Dong, Gang Chen
Format: Article
Language:English
Published: Elsevier 2020-06-01
Series:Biomedicine & Pharmacotherapy
Subjects:
Intracerebral hemorrhage
Luteolin
TRAF6
NF-κB
Neuroinflammation
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332220302353

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http://www.sciencedirect.com/science/article/pii/S0753332220302353

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