In vivo identification and characterization of CD4⁺ cytotoxic T cells induced by virulent Brucella abortus infection.

CD4(+) T cells display a variety of helper functions necessary for an efficient adaptive immune response against bacterial invaders. This work reports the in vivo identification and characterization of murine cytotoxic CD4(+) T cells (CD4(+) CTL) during Brucella abortus infection. These CD4(+) CTLs...

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Bibliographic Details
Main Authors: Anna Martirosyan, Kristine Von Bargen, Vilma Arce Gorvel, Weidong Zhao, Sean Hanniffy, Johnny Bonnardel, Stéphane Méresse, Jean-Pierre Gorvel
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/24367519/pdf/?tool=EBI