Combining gene signatures improves prediction of breast cancer survival.

BACKGROUND: Several gene sets for prediction of breast cancer survival have been derived from whole-genome mRNA expression profiles. Here, we develop a statistical framework to explore whether combination of the information from such sets may improve prediction of recurrence and breast cancer specif...

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Bibliographic Details
Main Authors: Xi Zhao, Einar Andreas Rødland, Therese Sørlie, Bjørn Naume, Anita Langerød, Arnoldo Frigessi, Vessela N Kristensen, Anne-Lise Børresen-Dale, Ole Christian Lingjærde
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3053398?pdf=render