Antitumor Efficacy of Intravesical BCG, Gemcitabine, Interferon-α and Interleukin-2 as Mono- or Combination-Therapy for Bladder Cancer in an Orthotopic Tumor Model

Objective To reduce adverse effects and improve efficacy of intravesical BCG for bladder cancer, alternative treatment options were investigated in an orthotopic rat tumor model. Methods Superficial bladder cancer was established in syngeneic female rat bladders by instillation of AY-27 cells. Anima...

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Bibliographic Details
Main Authors: Zhengwen Xiao, Erich Hanel, Allan Mak, Ronald B. Moore
Format: Article
Language:English
Published: SAGE Publishing 2011-01-01
Series:Clinical Medicine Insights: Oncology
Online Access:https://doi.org/10.4137/CMO.S7658