An optimized protocol for a standardized, femoral osteotomy model to study fracture healing in mice

Summary: Fracture healing represents a dynamic and complex process which depends on the balanced activities of a broad array of different cell types and signaling pathways. Here, we describe a femoral osteotomy protocol for mice, using an external fixator to stabilize the fractured bone. Depending o...

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Bibliographic Details
Main Authors: Shan Jiang, Paul Knapstein, Antonia Donat, Serafeim Tsitsilonis, Johannes Keller
Format: Article
Language:English
Published: Elsevier 2021-09-01
Series:STAR Protocols
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2666166721005049