Tropism of pandemic 2009 H1N1 influenza A virus

Substitutions at the receptor binding site of the pandemic H1N1 2009 influenza A virus (H1N1pdm) hemagglutinin (HA) gene may be critical in determining whether a virus binds to human or avian receptors. Previous reports suggest that HA Gly222 and/or Arg223 allow viruses to bind preferentially to the...

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Bibliographic Details
Main Authors: Ririn eRamadhany, Mayo eYasugi, Shota eNakamura, Tomo eDaidoji, Yohei eWatanabe, Kazuo eTakahashi, Kazuyoshi eIkuta, Takaaki eNakaya
Format: Article
Language:English
Published: Frontiers Media S.A. 2012-04-01
Series:Frontiers in Microbiology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fmicb.2012.00128/full