Inhibition or knockdown of ABC transporters enhances susceptibility of adult and juvenile schistosomes to Praziquantel.

Inhibition or knockdown of ABC transporters enhances susceptibility of adult and juvenile schistosomes to Praziquantel.

Parasitic flatworms of the genus Schistosoma cause schistosomiasis, a neglected tropical disease that affects hundreds of millions. Treatment of schistosomiasis depends almost entirely on the drug praziquantel (PZQ). Though essential to treating and controlling schistosomiasis, a major limitation of...

Full description

Bibliographic Details
Main Authors: Ravi S Kasinathan, Lalit Kumar Sharma, Charles Cunningham, Thomas R Webb, Robert M Greenberg
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-10-01
Series:PLoS Neglected Tropical Diseases
Online Access:http://europepmc.org/articles/PMC4199547?pdf=render

Internet

http://europepmc.org/articles/PMC4199547?pdf=render

Similar Items