Pharmacokinetics of Chlorin e6-Cobalt Bis(Dicarbollide) Conjugate in Balb/c Mice with Engrafted Carcinoma

Pharmacokinetics of Chlorin e6-Cobalt Bis(Dicarbollide) Conjugate in Balb/c Mice with Engrafted Carcinoma

The necessary precondition for efficient boron neutron capture therapy (BNCT) is control over the content of isotope 10B in the tumor and normal tissues. In the case of boron-containing porphyrins, the fluorescent part of molecule can be used for quantitative assessment of the boron content. Study O...

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Bibliographic Details
Main Authors: Arthur B. Volovetsky, Vladimir S. Sukhov, Irina V. Balalaeva, Varvara V. Dudenkova, Natalia Yu. Shilyagina, Аlexey V. Feofanov, Anastasija V. Efremenko, Mikhail A. Grin, Andrey F. Mironov, Igor B. Sivaev, Vladimir I. Bregadze, Anna V. Maslennikova
Format: Article
Language:English
Published: MDPI AG 2017-11-01
Series:International Journal of Molecular Sciences
Subjects:
boron neutron capture therapy
fluorescent microscopy
boron content
MS-ICP
simple multichamber model
chlorin e6 derivatives
Online Access:https://www.mdpi.com/1422-0067/18/12/2556

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https://www.mdpi.com/1422-0067/18/12/2556

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