Exploring targeting peptide-shell interactions in encapsulin nanocompartments

Abstract Encapsulins are recently discovered protein compartments able to specifically encapsulate cargo proteins in vivo. Encapsulation is dependent on C-terminal targeting peptides (TPs). Here, we characterize and engineer TP-shell interactions in the Thermotoga maritima and Myxococcus xanthus enc...

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Bibliographic Details
Main Authors: Wiggert J. Altenburg, Nathan Rollins, Pamela A. Silver, Tobias W. Giessen
Format: Article
Language:English
Published: Nature Publishing Group 2021-03-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-84329-z