Inducing cell death in vitro in cancer cells by targeted delivery of cytochrome c via a transferrin conjugate.

One of the major drawbacks of many of the currently used cancer drugs are off-target effects. Targeted delivery is one method to minimize such unwanted and detrimental events. To actively target lung cancer cells, we have developed a conjugate of the apoptosis inducing protein cytochrome c with tran...

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Bibliographic Details
Main Authors: Manoj Saxena, Yamixa Delgado, Rohit Kumar Sharma, Shweta Sharma, Solimar Liz Ponce De León Guzmán, Arthur D Tinoco, Kai Griebenow
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5896948?pdf=render