Epidermal to Mesenchymal Transition and Failure of EGFR-Targeted Therapy in Glioblastoma

Glioblastoma multiforme (GBM), the most common primary brain tumor in adults, is almost never curable with the current standard treatment consisting of surgical resection, irradiation and temozolomide. The prognosis remains poor despite undisputable advances in the understanding of this tumor’s mole...

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Bibliographic Details
Main Authors: Marc-Eric Halatsch, Christian Rainer Wirtz, Richard Eric Kast, Andrej Pala, Georg Karpel-Massler
Format: Article
Language:English
Published: MDPI AG 2012-05-01
Series:Cancers
Subjects:
Online Access:http://www.mdpi.com/2072-6694/4/2/523