Crosstalk Between ATP-P2X7 and Adenosine A2A Receptors Controlling Neuroinflammation in Rats Subject to Repeated Restraint Stress

Crosstalk Between ATP-P2X7 and Adenosine A2A Receptors Controlling Neuroinflammation in Rats Subject to Repeated Restraint Stress

Depressive conditions precipitated by repeated stress are a major socio-economical burden in Western countries. Previous studies showed that ATP-P2X7 receptors (P2X7R) and adenosine A2A receptors (A2AR) antagonists attenuate behavioral modifications upon exposure to repeated stress. Since it is unkn...

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Bibliographic Details
Main Authors: Liliana Dias, Cátia R. Lopes, Francisco Q. Gonçalves, Ana Nunes, Daniela Pochmann, Nuno J. Machado, Angelo R. Tomé, Paula Agostinho, Rodrigo A. Cunha
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-03-01
Series:Frontiers in Cellular Neuroscience
Subjects:
ATP P2X7 receptor
adenosine A2A receptor
stress
behavior
microglia
neuroinflammation
Online Access:https://www.frontiersin.org/articles/10.3389/fncel.2021.639322/full

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https://www.frontiersin.org/articles/10.3389/fncel.2021.639322/full

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