Paraquat poisoning induces TNF-α-dependent iNOS/NO mediated hyporesponsiveness of the aorta to vasoconstrictors in rats.

Paraquat poisoning induces TNF-α-dependent iNOS/NO mediated hyporesponsiveness of the aorta to vasoconstrictors in rats.

Paraquat is a toxic herbicide that may induce acute lung injury, circulatory failure and death. The present work aimed at investigating whether there is systemic inflammation and vascular dysfunction after paraquat exposure and whether these parameters were related. There was neutrophilia and accumu...

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Bibliographic Details
Main Authors: Rosária D Aires, Luciano S A Capettini, Josiane F Silva, Maria da Glória Rodrigues-Machado, Vanessa Pinho, Mauro M Teixeira, Steyner F Cortes, Virginia S Lemos
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/24039983/?tool=EBI

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https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/24039983/?tool=EBI

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