Vandetanib versus Cabozantinib in Medullary Thyroid Carcinoma: A Focus on Anti-Angiogenic Effects in Zebrafish Model

Vandetanib versus Cabozantinib in Medullary Thyroid Carcinoma: A Focus on Anti-Angiogenic Effects in Zebrafish Model

Medullary thyroid carcinoma (MTC) is a tumor deriving from the thyroid C cells. Vandetanib (VAN) and cabozantinib (CAB) are two tyrosine kinase inhibitors targeting REarranged during Transfection (RET) and other kinase receptors and are approved for the treatment of advanced MTC. We aim to compare t...

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Bibliographic Details
Main Authors: Silvia Carra, Germano Gaudenzi, Alessandra Dicitore, Davide Saronni, Maria Celeste Cantone, Alice Plebani, Anna Ghilardi, Maria Orietta Borghi, Leo J. Hofland, Luca Persani, Giovanni Vitale
Format: Article
Language:English
Published: MDPI AG 2021-03-01
Series:International Journal of Molecular Sciences
Subjects:
medullary thyroid carcinoma (MTC)
zebrafish
tumor xenograft
tyrosine kinase inhibitors (TKIs)
angiogenesis
cabozantinib
Online Access:https://www.mdpi.com/1422-0067/22/6/3031

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https://www.mdpi.com/1422-0067/22/6/3031

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