Regulation of Bile Acid and Cholesterol Metabolism by PPARs

Bile acids are amphipathic molecules synthesized from cholesterol in the liver. Bile acid synthesis is a major pathway for hepatic cholesterol catabolism. Bile acid synthesis generates bile flow which is important for biliary secretion of free cholesterol, endogenous metabolites, and xenobiotics. Bi...

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Bibliographic Details
Main Authors: Tiangang Li, John Y. L. Chiang
Format: Article
Language:English
Published: Hindawi Limited 2009-01-01
Series:PPAR Research
Online Access:http://dx.doi.org/10.1155/2009/501739