Regulation of Bile Acid and Cholesterol Metabolism by PPARs
Bile acids are amphipathic molecules synthesized from cholesterol in the liver. Bile acid synthesis is a major pathway for hepatic cholesterol catabolism. Bile acid synthesis generates bile flow which is important for biliary secretion of free cholesterol, endogenous metabolites, and xenobiotics. Bi...
Main Authors: | Tiangang Li, John Y. L. Chiang |
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Format: | Article |
Language: | English |
Published: |
Hindawi Limited
2009-01-01
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Series: | PPAR Research |
Online Access: | http://dx.doi.org/10.1155/2009/501739 |
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